For Arsenal, failure to defeat Wigan Athletic on Tuesday would leave their hopes of a 16th season in the Champions League in severe jeopardy; for Wigan Athletic, anything other than a win would quickly sour the taste of a memorable FA Cup final shock.
Images from the English Premier League matches played across England on Sunday.
Runaway Premier League leaders Manchester City beat champions Chelsea 1-0 at the Etihad Stadium on Sunday to extend their lead to 18 points and leave the London side further adrift from the Champions League qualification spots.
IMAGES from an exciting Europa League semi-final first leg match played at Emirates Stadium on Thursday
Manchester City moved back into third place and almost guaranteed Champions League qualification thanks to a 3-1 home victory against West Bromwich Albion on Tuesday at the Etihad Stadium.
Arsenal will need no reminder of the pitfalls in store for them at Wembley Stadium on Saturday where they will be favourites to beat Hull City in the FA Cup final and claim their first silverware for nine years.
French striker Thierry Henry will take over as Arsenal captain following Patrick Vieira's transfer to Juventus
Arsenal may be down but manager Arsene Wenger said they are very definitely not yet out of the hunt for major honours this season, which they can prove when they face Liverpool for the third time in a week on Tuesday. Wenger takes his weary men to Anfield for the second leg of their Champions League quarter-final after two 1-1 draws with Liverpool at the Emirates Stadium in the last few days.
Chelsea manager Jose Mourinho is "disrespectful" and a "bully" for describing Arsene Wenger "a specialist in failure", former Arsenal goalkeeper Bob Wilson said on Sunday.
Lionel Messi didn't enjoy his time with the Ligue 1 side Paris Saint Germain.
Manchester City tore Arsenal apart for the second time in five days on Thursday, beating them 3-0 on a freezing night at The Emirates to restore their 16-point lead as they close in on the Premier League title.
Arsene Wenger remains confident his side can complete the double over Sevilla and finish top of Champions League Group.
Arsenal will put one of the best Champions League records on the line when they face Olympiakos Piraeus in a showdown for second spot in Group F on Wednesday.
Gunners skipper Cesc Fabregas has no doubt that Arsenal can beat Chelsea and roar right back into the title race.
AC Milan survived an almighty scare against a rejuvenated Arsenal to scrape into the UEFA Champions League quarter-finals 4-3 on aggregate on Tuesday despite being thrashed 3-0 by the London side.
Arsenal are seeking compensation from the Dutch Football Federation for the injury sustained by striker Robin van Persie last month, manager Arsene Wenger said.
A controversial Radamel Falcao effort gave Porto a 2-1 win over Arsenal in their Champions League last-16 first leg but the English side will take heart from Sol Campbell's away goal on his return to the tournament after four years.
Arsenal defender Thomas Vermaelen suffered a suspected broken leg during the goalless draw at Aston Villa in the Premier League on Wednesday.
Russia forward Andrei Arshavin completed his transfer to Arsenal from Zenit St Petersburg on Tuesday, the English Premier League club said. British media reported he has agreed a three-and-a-half-year contract and has cost Arsenal around 15 million pounds.
Croatia striker Eduardo has signed a new long-term contract with Arsenal, the Premier League club said on Wednesday.
Arsene Wenger can be excused a little smugness as he prepares his Arsenal side for Wednesday's Champions League quarter-final second leg at home to Villarreal as a bleak-looking season has suddenly burst into bloom. Last week's 1-1 draw in Spain makes Arsenal favourites to progress to a semi-final against either holders Manchester United or Porto while on Saturday they face Chelsea in the last four of the FA Cup at Wembley.
Substituted into the English Premier League club's third round FA Cup match against Leeds United on 68 minutes with the score at 0-0, the on-loan striker took just 10 minutes to break the deadlock with the winning goal for his beloved Arsenal.
Arsenal had to come from behind after Sergio Aguero scored his 30th goal of the season for City in the 63rd minute, racing away on to a pass from Yaya Toure.
"Tomorrow we don't play six points against zero. We play at 7.45, at 0-0 with 90 minutes to go," he said.
Arsenal had to come from behind twice to beat Leicester City 4-3 in a thriller as the English Premier League season got off to a flying start on Friday with Arsene Wenger's substitutions turning the match around at The Emirates.
A draw with Leicester City on Saturday will make them the first top-flight club since Preston North End to finish their campaign unbeaten.
Holders Arsenal kept up their bid for a hat-trick of FA Cup trophies, marching into the quarter-finals as Olivier Giroud and Theo Walcott netted twice in a 4-0 replay win at second-tier Hull City on Tuesday.
Robert Pires and Jermaine Pennant fired hat-tricks in a 6-1 win, a dress rehearsal for next week's FA Cup final.
Arsenal's early-season soap opera took more twists and turns on Tuesday with midfielder Samir Nasri poised to join Manchester City and manager Arsene Wenger given clearance by UEFA to delay his European ban.
Arsenal captain Cesc Fabregas will miss Sunday's League Cup final against Birmingham City at Wembley with a hamstring injury, the club said on Thursday.
The German goalkeeper remains hopeful of playing at the 2006 World Cup, despite the loss of his place at Arsenal to Manuel Almunia.
Arsenal missed the chance to heighten the congestion at the top of the Premier League and suffered fresh injury blows when a frustrating 1-1 draw at Norwich City failed to take them alongside leaders Manchester City and Leicester City on Sunday.
Jens Lehmann may be allowed to leave Arsenal next month if the right offer is received, manager Arsene Wenger said.
France and Arsenal forward Olivier Giroud has fuelled speculation that Jamie Vardy is on his way to the Gunners by saying he has heard the Leicester City striker is keen to move.
English Premier League club Arsenal were the only club not to have won the Champions League to be placed among the top seeds for the 2012/2013 draw, later on Thursday (1545GMT).
Tottenham Hotspur reached the League Cup final after an emphatic 5-1 victory over Arsenal.
Arsenal resume battle with Manchester United at the top of the Premier League on Saturday.
